|
Symbol Name ID |
Ret
ret proto-oncogene MGI:97902 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Elevated circulating calcitonin concentration |
Increased circulating cortisol level |
Parathyroid adenoma |
Parathyroid hyperplasia |
Hyperparathyroidism |
Nodular goiter |
Neoplasm of the thyroid gland |
Medullary thyroid carcinoma |
Thyroid C cell hyperplasia |
Pheochromocytoma |
| Disease(s) Associated with RET | ||||||||||
| familial medullary thyroid carcinoma | ||||||||||
| Hirschsprung's disease | ||||||||||
| multiple endocrine neoplasia type 2A | ||||||||||
| multiple endocrine neoplasia type 2B | ||||||||||
| pheochromocytoma |
| Mouse Phenotypes | abnormal submandibular gland morphology |
endocrine/exocrine gland phenotype |
abnormal adrenal gland morphology |
adrenal cortical hyperplasia |
abnormal adrenal medulla morphology |
adrenergic chromaffin cell hyperplasia |
abnormal thyroid gland morphology |
thyroid gland hyperplasia |
ectopic ovary |
seminiferous tubule degeneration |
cryptorchism |
ectopic testis |
increased pheochromocytoma incidence |
increased thyroid adenoma incidence |
|
| Availability | Mouse Genotype | ||||||||||||||
| Rettm1Cos/Rettm1Cos | * | ||||||||||||||
| Rettm1Jmi/Rettm1Jmi | |||||||||||||||
| Rettm2.1Cos/Rettm2.1Cos | |||||||||||||||
| Rettm8(RET)Jmi/Rettm8(RET)Jmi | |||||||||||||||
| Rettm11(RET)Jmi/Rettm11(RET)Jmi | |||||||||||||||
| Rettm1Cos/Rettm2.1Cos | * | ||||||||||||||
| Rettm1Giro/Ret+ | |||||||||||||||
| Rettm2.1Cos/Ret+ | |||||||||||||||
| Rettm3.1(RET)Jmi/Ret+ | |||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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